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Multiple Myeloma Overview – Signs and Symptoms

Multiple myeloma is cancer in the plasma cells of the bone marrow. These cells are a kind of white blood cells that are the protein-making cells. These cells make the different antibodies for the body to stay immune. In multiple myeloma, these plasma cells start making only one type of abnormal protein instead of the different kinds of antibodies that are required by the body. The abnormal type of protein cells is referred to as monoclonal or M protein.

Causes of multiple myeloma

While any definite cause for multiple myeloma is indefinite, there are some factors that can trigger the production of abnormal protein by the plasma cells. Some of these factors include harmful radiation, toxic chemicals, certain viruses, and immunity disorders. Genetic factors and family history are also important factors.

Signs and symptoms of multiple myeloma

It is common to find asymptomatic patients with multiple myeloma with absolutely no signs or symptoms. But as the illness advances, there are a number of symptoms that show up. Here is an overview of the signs and symptoms of multiple myeloma.

  • Bone problems like pain that are experienced more commonly in parts like hips, skull, and the back. Other bone problems that may indicate multiple myeloma include bone weakness all over the body or at the site of plasmacytoma. Patients with multiple myeloma may also sometimes fracture their bones even if it’s a minor injury.
  • Low blood counts are looked at as signs for multiple myeloma. A low red blood cell count can cause anemia, which is characterized by weakness and reduced ability to exercise or do an intense physical activity.
  • Leucopenia, a condition caused to lessen white blood cells lowers the immunity against infections. When the patient has low blood platelets, he is prone to bleeding a lot even it is a small cut or wound.
  • High blood levels of calcium can show multiple signs like extreme thirst, frequent urination, severe constipation, weakness, and loss of appetite, among the others.
  • Sudden severe back pain and muscle weakness in the legs can occur due to the weak bones collapsing in the spine, which causes a pressure on the spinal nerves. This is one of the multiple myeloma signs and symptoms that need immediate medical attention.
  • Weakness and numbness in nerves caused due to the abnormal proteins that are toxic to the nerves.
  • A higher number of M proteins can make the blood thicker. This thickening, also referred to as hyperviscosity, can result in slower blood flow to the brain and cause confusion, dizziness, and stroke-like symptoms.
  • The abnormal protein may also cause damage to the kidney and hinder its ability to dispose of the excess salt and other waste efficiently.

It is important to note that all or some of these signs and symptoms are not always indicative of multiple myeloma and may be due to other medical conditions as well. The best way to know is by seeing a doctor to rule out the possibility of multiple myeloma.

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ADHD is characterized as a neurodevelopmental disorder that impacts a patient’s behavior and brain. While ADHD can’t be cured, doctors typically recommend a combination of prescription medication and lifestyle changes to keep behavioral symptoms under control. Keep in mind that ADHD affects every patient differently, so no one treatment works for everyone.


Here are the most common treatment options for ADHD:

Therapy

Cognitive behavioral therapy is often recommended in combination with other ADHD treatments to teach patients to manage their symptoms. Therapy can teach patients techniques for dealing with stress, memory retention, time management skills, anger control, and even improve self image.z

Stimulant medications

ADHD stimulants, such as Methylphenidates (i.e., Ritalin, Concerta, and Quillivant), Amphetamines (i.e., Zenzedi, Dexedrine, and ProCentra), and mixed salt single-entity amphetamines (i.e., Mydayis) are prescribed to help manage symptoms while altering the brain to help patients focus better and control impulsive behavior.  These drugs are typically prescribed at low doses in short acting (that work for up to 4-hours) and long acting forms (that work for up to 12-hours) to see how the brain responds, and increased as necessary. Many of these medications come in both short- and long-acting forms. Stimulants of any kind should be taken according to doctor’s orders and never stopped suddenly. Many ADHD stimulants causes side effects, such as headache, dry mouth, and lack of appetite.

Non-stimulant medications

If your body doesn’t respond well to stimulant drugs, non-stimulants (i.e., atomoxetine) provide another option. Non-stimulants alter brain chemicals to manage impulse control and hyperactive behavior. Like, stimulants, non-stimulants also often cause side effects such as drowsiness, dry mouth, and headache.

ADHD support

Participating in an ADHD support group can help patients with feelings of isolation. Many of these groups offer discussion and activities that focus on improving self esteem while teaching participants anger management, positive social skills, and techniques to deal with impulsive behavior. They may also feature stress management tools, or yoga and meditation to help with anxiety.

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fashion

Fashion is such an individualized thing. Everyone is different and therefore everyone has personal preferences when it comes to different types of dresses. One thing is true though; it’s important to have at least one versatile and flattering dress in your wardrobe. When determining what type to choose, there are several styles to consider that can be appropriate for different types of events and different figures.

Women today attend many events that require dressing up for the occasion. These may include weddings, dates, parties, work events, and brunch. When looking to buy a dress to suit a wide range of occasions, here are some flattering options for all ages and body types:

1. Wrap dresses

Wrap dresses are exactly what they sound like. These dresses are pulled together with a front closure. One side of the dress is wrapped across the front and then either goes behind the back part of the waist to either be attached by buttons or tied. The construction of this dress creates a v-neck front. It also accentuates the curves of the wearer in the chest area.

2. Maxi dresses

Maxi dresses are a great option for many occasions. They are long and go to the floor. Generally, they are designed to fit the body on the top, and then be flowy and long on the bottom. The fun thing about them is they can feature many different necklines and come in various patterns and colors. This makes them very individualized to the person.

3. A-Line dresses 

A-line dresses are named after the shape they take on the body, which is an “A”. They fit to the top part of the body and begin to flare gradually out at the waist and hips, becoming wider as the hem progresses. A-line clothing can be found not just in dresses, but also in coats and skirts.

4. Little black dresses

Everyone has heard of the little black dress. This is such a versatile option that can be found in your closet. It can be dressed up or down for numerous types of events. As a general design, it is usually a simple dress that tends to be quite short. The elegance and simplicity create a fairly blank canvas that allows you to create the exact type of look that you want. Many designers provide limitless options for this much-needed wardrobe essential. Victoria Beckham cocktail dresses are one good brand to consider.

5. Mini dresses

A mini, or short dress that hangs just above the knees is a common style. This design became popular in the 1920’s. It was later revitalized in the 1960s, and has remained an integral part of many wardrobes ever since. A mini shift style dress is a loose-fitting dress that is very comfortable and does not fit tightly around the waist or any part of the body. It is loose at both the hips and the waist so the dress falls loosely down from the shoulders all the way down to the bottom of the dress. Darts are generally located in the bust area. It is a straight silhouette that can be flattering for those that have bodies that are shaped more like a column and it also elongates petite figures as it shows off the legs. 

When shopping for dresses, every designer has his or her own individual interpretation. It is fun, and a great idea to look at the individual designers and fashion forward celebrities to find the one that fits your aesthetic most closely. Also, remember that designers also have many other clothing options. As an example, when looking at what stars wear, like Kourtney Kardashian or Victoria Beckham (blouses, skirts, dresses and pants), you might find a designer that the star tends to wear a lot that you can draw inspiration from.

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The right handbag can really accentuate your outfit of the day. There are also many styles and functions for different handbags. You could have a handback that works as a daily driver – a bag that you take to run errands or to the store. You could also have a bag that’s perfect for traveling or for a night out. Whatever the case may be, these are five handbags that are sure to be everywhere this season:

1. Versace Chunky Chain Bag

This Versace bag features a chunky chain which really is the stand out feature on this bag. The chain provides a cool effect when you wear it, that really draws your eyes to it. In typical Versace fashion, the chunky chain bag is made of high quality materials and is a great value for the price.

2. Lanvin Puffy Cloud Bag

The Lanvin Puffy Cloud Bag is another bag you’ll be seeing a lot of in 2021. This bag is one of the top trends in handbags right now, and for good reason. The Lanvin quality is apparent and you can really wear this on any occasion, formal or casual.

3. Stella McCartney Hobo Bag

The Stella McCartney Hobo bag has a relaxed look about it. It appears slightly slouched in nature, which provides a really cool effect. This bag can be dressed up for a nice, formal event or dressed down for a nice casual day. This bag is incredibly versatile and provides enough room for all of your belongings. It has two slip pockets and an interior compartment for maximum storage. This is one bag that can really do it all.

4. Bottega Veneta Fisherman Shoulder Bag

The Bottega Veneta Fisherman Shoulder Bag is extremely trendy right now, and for good reason. The bag features a scale like pattern which is the standout feature. It also features a shoulder strap for great versatility and a super comfortable wear. The bag features high quality materials and enough room to keep all your belongings stored nicely. This bag leans a bit casual but is a great bag if you’re looking to make a statement throughout the day.

5. Fendi Fluffy Feathers Bag

The Fendi fluffy feathers bag is a bag that’s sure to make a statement. This bag is made of high quality materials, in typical Fendi fashion. The fluffy feathers bag is covered in ostrich feathers. This bag is incredibly unique and will turn all the heads. It’s also very versatile in that all of the straps are detachable so you could wear this as a shoulder bag or as a little handheld purse. When you pair this with a stunning dress, you will be sure to turn heads at any formal event or night out on the town.

These bags can be found at many of your favorite retailers and department stores. Make sure to shop Saks Fifth Avenue bags for the latest in deals and trends for the 2021 year.

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Jewelry is the one of the best accent pieces for any outfit you choose to wear. The right necklace, or the right bracelet, can really put the finishing touch on an amazing outfit. You may opt to wear a necklace on a night out, or a set of bangles to run some errands. Either way there are a few styling hacks to help maximize your jewelry. Here are six jewelry styling hacks to follow:

1. Use earrings for a pop of color
It can be a great idea to match a few pieces of jewelry, however, when they’re all very similar in style and color, they can really blend together. To solve this issue, try using earrings to create that pop of color. Earrings can really balance out an outfit

2. Know when it’s too much
Jewelry can provide a great accent to your favorite outfit but you need to be careful you don’t overdo it. By having too much, you’re really taking away from the effect your jewelry adds to your outfit

3. Personalize with statement jewelry
Something like customized wrist bracelets can be super personal. This can be a piece that no one has that truly stands out on its own. These are often hard to duplicate because they’re one of a kind and customized. Check Kay Jewelers clearance sale and see if there’s anything that you could customize and make truly unique

4. Minimal jewelry with patterned clothing
When your outfit is full of patterns, it’s already incredibly loud. Something like stripes or plaid can be a super powerful statement in itself so when picking out jewelry, make sure to keep it minimal. When it’s overdone it can have the opposite effect of what you’re looking for. One simple necklace or bracelet can be a nice, quick addition to a loud outfit with many patterns

5. Create layers with necklaces and bangles
Sometimes when we wear jewelry it can be hard to get the most out of it. Sometimes our jewelry is too thin and won’t really pop with our outfits. That’s where layering comes into play. By layering bangles you can create a super nice, textured set of bracelets that will surely stand out. With necklaces, you want to look at the style and length. By mixing and layering different necklace lengths, you can create the illusion of a much bigger piece and have them all flow together seamlessly. Either way, you really can’t go wrong with layering

6. Mix metals in jewelry
Most jewelry is made of various metals like gold, silver, and platinum. By combining different metals, you can really make them pop. When mixing and matching gold and silver you really create a palate with different colors and materials. It helps them stand out. When you wear all your jewellery in one material or one color, the pieces tend to blend in with each other. Mixing metals will help your pieces to really make a statement

When choosing jewelry, make sure to follow these 6 hacks for best results!

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